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In the late 1960s, just for a lark, graduate student Eddie Jessup, known for being unconventional, brilliant and slightly mad, conducts experiments with an isolation chamber, using himself as the subject. His experiences in the chamber cause him to hallucinate, much of the imagery being religious-based although hes not religious. Seven years later, he is a respected full professor in the Harvard Medical School. Believing he has lost his edge and fallen into an unwanted state of respectability, Eddie decides to resume his work with sensory deprivation, this time using hallucinogens, specifically untested ones used in mystical Mexican rituals, to enhance the isolation-take experience. After initial tests, he claims he entered an alternate physical and mental state. Although unbelieving of Eddies claims, his colleagues Arthur Rosenberg and Mason Parrish, as well as Eddies wife Emily, herself a respected academic, are concerned for Eddies well being. However, if Eddies claims are indeed true, he could do irreparable harm to himself and others around him, especially if his altered states are uncontrollable.
Respected scientist and psychology professor Edward Jessup decides to combine his experiments in sensory deprivation tanks with powerful hallucinogenic drugs, convinced it may help him unlock different states of consciousness. The experiments are a success at first, but as Jessup continues his work he begins to experience altered mental and physical states. As he spends more time in sensory deprivation, his grip on reality slips away.
William Hurt
Eddie Jessup
Blair Brown
Emily Jessup
Bob Balaban
Arthur Rosenberg
Charles Haid
Mason Parrish
Thaao Penghlis
Eccheverria
Miguel Godreau
Primal Man
Dori Brenner
Sylvia Rosenberg
Peter Brandon
Hobart
Charles White-Eagle
The Brujo
Drew Barrymore
Margaret Jessup
Megan Jeffers
Grace Jessup
Jack Murdock
Hector Orteco
Francis X. McCarthy
Obispo
Deborah Baltzell
Schizophrenic Patient
Evan Richards
Young Rosenberg
Hap Lawrence
Endocrinology Fellow
John Walter Davis
Medical Technician
Cynthia Burr
Parrish's Girl
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