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1969. Dr. Malcolm Sayer is hired as a clinical physician at a local hospital in the Bronx, despite only having a research background. The job is not ideal on his side as he has difficulties relating to people which is the reason he has focused on research projects not involving human subjects, while the hospital hires him somewhat out of desperation in not finding anyone else with the qualifications who wants the job. Most of his patients are in a semi-catatonic state and are housed in what some of the orderlies coin the "garden" ward, where all they can do for the patients is water and feed them. He notices that some of the patients, despite their generally catatonic state, respond in unusual ways to certain stimuli. In doing some research, he also finds that some common bonds between these patients are that they suffered from encephalitis in the 1920s or 1930s, and that their physical states are like they have Parkinsons disease frozen in time. As such, he is able to convince, albeit reluctantly, his skeptical boss, Dr. Kaufman, to administer an expensive experimental drug therapy on only one patient with family consent. That patient is forty-one year old Leonard Lowe, who has been in his current state since he was eleven years old, and who has been supported by his loving mother through all these years. As the drug therapy "awakens" Leonard, there are several issues that come into play. Malcolm has to try and convince Kaufman and the hospital administration to extend the therapy to the other patients. Despite not knowing the long term effects, Leonard, who was aware of his surroundings through his catatonic state, may have mixed emotions about his situation, wanting both to be treated as human being and an experiment guinea pig to ensure that what is happening benefits him and others in the long run. Mrs. Lowe may be unprepared for the new Leonard, she expecting who she remembers as a sweet eleven year old boy. Through all these issues, what may be the most illuminating issue for Malcolm is the need to stimulate the human spirit, including his own in dealing with people around him.
A new doctor finds himself with a ward full of catatonic patients. He is disturbed by them and the fact that they have been catatonic for decades with no hope of any cure. When he finds a possible chemical cure he gets permission to try it on one of them. When the first patient awakes, he is now well into his 50s having gone into a catatonic state at 20 years of age. The film then delights in the new awareness of the patients and then on the reactions of their relatives to the changes in the newly awakened.
Robert De Niro
Leonard Lowe
Robin Williams
Dr. Malcolm Sayer
Julie Kavner
Eleanor Costello
Ruth Nelson
Mrs. Lowe
John Heard
Dr. Kaufman
Penelope Ann Miller
Paula
Alice Drummond
Lucy
Judith Malina
Rose
Barton Heyman
Bert
George Martin
Frank
Anne Meara
Miriam
Richard Libertini
Sidney
Laura Esterman
Lolly
Dexter Gordon
Rolando
Jayne Haynes
Frances
Le Clanché du Rand
Magda
Yusef Bulos
Joseph
Steven Randazzo
Luis
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