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Charly is an adult male with a cognitive disability, struggling to survive in the modern world. His frequent attempts at learning, reading and writing prove difficult, and he is the subject of cruel pranks at the bakery where he does minor janitorial work. His teacher, Mrs. Kinnian, enrolls Charly in a clinical study where he is observed by a surgeon and a psychologist who have Charly "race" a mouse named Algernon, solving mazes. Algernon is usually the winner, thanks to an experiment involving brain proteins that greatly raised his intelligence. The experiment proceeds with surgery on Charly, who at first does not seem affected. However, he quickly becomes more logically advanced, soon becoming a pure genius. Emotional and intra-personal consequences are involved as Charly and his teacher become increasingly attached to one another. But when Charly gradually suspects the consequences of the experiment, he struggles with whether or not the procedure was a good idea.
The mentally disabled Charly is a sweet adult that works as janitor in a bakery and tries to learn how to read and write in a night school. His teacher, Mrs. Alice Kinnian, brings Charly to participate in an experiment in a clinic led by the surgeon Dr. Nemur and the psychologist Dr. Straus. Charly has to race through mazes with a mouse named Algernon that was submitted to a brain surgery and he always lose. But Mrs. Kinnian convinces Dr. Nemur to operate Charly that increases his intelligence to a genius. But soon he learns the effects of the experiment and questions the result.
Cliff Robertson
Charly Gordon
Claire Bloom
Alice Kinian
Lilia Skala
Dr. Anna Straus
Leon Janney
Dr. Richard Nemur
Ruth White
Mrs. Apple
Dick Van Patten
Bert
Edward McNally
Gimpy
Barney Martin
Hank
William Dwyer
Joey
Dan Morgan
Paddy
Marianna Case
Young Woman
Leon Collins
Tap Dancer
Harry Cooper
Conference Attendee
Frank Dolan
Eddie
Randee Lynne Jensen
Extra
Ralph Nelson
Convention Speaker
Donald Warnock
Conference Attendee
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