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After a long absence, Chris McCormick returns to his quiet hometown of Prosperity, Arizona, to reopen his late fathers mines. However, a chemical spill and lethal toxic waste have created an unstoppable army of giant spiders who prey on the unsuspecting locals, turning Prosperity into an endless buffet. Now, its up to Chris; Sheriff Sam Parker; her son Mike; Sams plucky daughter, Ashley; the conspiracy theorist, Harlan, and a handful of survivors to stop the hairy menace, and save the town. But, who can stand in the way of the disgusting eight-legged freaks?
The residents of a rural mining town discover that an unfortunate chemical spill has caused hundreds of little spiders to mutate overnight to the size of SUVs. Its then up to mining engineer Chris McCormack and Sheriff Sam Parker to mobilize an eclectic group of townspeople, including the Sheriffs young son, Mike, her daughter, Ashley, and paranoid radio announcer Harlan, into battle against the bloodthirsty eight-legged beasts.
David Arquette
Chris McCormick
Kari Wuhrer
Sheriff Samantha Parker
Scott Terra
Mike Parker
Scarlett Johansson
Ashley Parker
Doug E. Doug
Harlan Griffith
Rick Overton
Deputy Pete Willis
Leon Rippy
Wade
Matt Czuchry
Bret
Jay Arlen Jones
Leon
Eileen Ryan
Gladys
Riley Smith
Randy
Matt Holwick
Larry
Jane Edith Wilson
Emma
Jack Moore
Amos
Roy Gaintner
Floyd
Don Champlin
Leroy
John Storey
Mark
David Earl Waterman
Norman
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