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Athena-1, a space station owned by gene manipulation company Energyne, is destroyed after a laboratory rat mutates and wreaks havoc. Dr. Kerry Atkins, the lone surviving crew member, is ordered by CEO Claire Wyden to retrieve research canisters containing a pathogen. Atkins is able to flee in the escape pod when the station implodes, but due to damage from the rat it disintegrates upon re-entry, killing her. The falling pieces leave a trail of debris across the United States, including the Everglades in Florida, where a canister is consumed by an American crocodile, and a forest in Wyoming, where a gray wolf is exposed to the pathogen. Primatologist Davis Okoye, a former US Army Special Forces soldier and member of an anti-poaching unit, works at the San Diego Wildlife Sanctuary. He has befriended a rare albino western lowland gorilla named George, having saved him from poachers, and communicates with George using sign language and hand gestures. At night, one of the canisters crash-lands in Georges habitat, and George is exposed to the pathogen..
Primatologist Davis (Dwayne Johnson) shares an unshakable bond with George, the extraordinarily intelligent silverback gorilla who has been in his care since he was young. When a greed-fueled corporations genetic experiment goes awry, George and other animals across the country are mutated into aggressive supercreatures who destroy everything in their path. In this adrenaline-filled ride, Davis tries to find an antidote, not only to halt a global catastrophe but also to save the fearsome creature who was once his friend.
Dwayne Johnson
Davis Okoye
Naomie Harris
Dr. Kate Caldwell
Malin Akerman
Claire Wyden
Jeffrey Dean Morgan
Harvey Russell
Jake Lacy
Brett Wyden
Joe Manganiello
Burke
Marley Shelton
Dr. Kerry Atkins
P.J. Byrne
Nelson
Demetrius Grosse
Colonel Blake
Jack Quaid
Connor
Breanne Hill
Amy
Matt Gerald
Zammit
Will Yun Lee
Agent Park
Urijah Faber
Garrick
Bruce Blackshear
Taylor
Jason Liles
George
Mac Wells
Communications Officer
Allyssa Brooke
Radar Officer
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