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The Rugrats and family become stranded on an island, and Stu Pickles (Jack Riley) is blamed. The kids wander off into the jungle, and Spike (Bruce Willis) loses his sense of smell due to sneezing. This becomes a problem when a clouded leopard named Siri (Chrissie Hynde) finds out about the babies and goes after them, and the situation only gets worse when the kids become trapped underwater with an amnesic Nigel Thornberry (Tim Curry), losing oxygen fast.
Jodi Carlisle
Marianne Thornberry
Lacey Chabert
Eliza Thornberry
Tim Curry
Nigel Thornberry
Elizabeth Daily
Tommy Pickles
Nancy Cartwright
Chuckie Finster
Kath Soucie
Phil DeVille
Dionne Quan
Kimi Finster
Cheryl Chase
Angelica Pickles
Joe Alaskey
Grandpa Lou Pickles
Tress MacNeille
Charlotte Pickles
Michael Bell
Drew Pickles
Melanie Chartoff
Didi Pickles
Julia Kato
Kira Finster
Phil Proctor
Howard DeVille
Jack Riley
Stu Pickles
Tara Strong
Dil Pickles
Cree Summer
Susie Carmichael
Danielle Harris
Debbie Thornberry
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