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A letter from Jane, who is nursing British troops, asks Tarzans help in obtaining a malaria serum extractable from jungle plants. Tarzan and Boy set out across the desert looking for the plants and wind up ruining a Germans attempt to capture a wild horse. They arrive in an Arab city and rescue a stranded American lady magician, sentenced to be hanged for carrying a secret message to the Sheik. To obtain the plants, Tarzan must fight prehistoric monsters, Nazis, and so on.
Jane is still in London working as a nurse in a military hospital. She asks Tarzan to get her some of the medicine they had used when Boy had developed fever and he sets off with Boy and Cheetah to the great desert to get the plants in question. Along the way, they meet Connie Bryce, a magician who had been entertaining troops in North Africa and has now been offered the opportunity entertain an Arab sheik. They make their way to the desert capital but find their leader under the influence of Nazis. Once there, Tarzan is charged with horse theft and imprisoned. Tarzan, Boy and Connie manage to escape and along the way encounter many strange creatures including giant lizards, killer spiders and a man-eating plant.
Johnny Weissmuller
Tarzan
Nancy Kelly
Connie Bryce
Johnny Sheffield
Boy
Otto Kruger
Paul Hendrix
Joe Sawyer
Karl Straeder
Lloyd Corrigan
Sheik Abdul El Khim
Robert Lowery
Prince Selim
Frank Puglia
Magistrate
Philip Van Zandt
Kushmet
Bobby Barber
Turban Vendor
John Berkes
Charlie
John Dehner
Prince Ameer
Dice
Jaynar
Frank Faylen
Achmed
George J. Lewis
Ali Baba Hassan
Nestor Paiva
Prison Guard
Syd Saylor
Bewildered Camel Herdsman
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