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Leonard is a 4th grader; his mother, Mrs. Mary Lou Helperman, is his teacher, and has been nominated for a teaching award. They plan a trip to Florida for the finals, but need to leave their dog, Spot, behind. Unknown to Mrs. Helperman, Spot has been masquerading as a boy, Scott, who is her star pupil. Spot wants nothing more than to be a real boy, and sees a way to this when mad scientist Ivan Krank appears on the Barry Anger show. Krank thinks he can turn animals into humans. Conveniently, his lab is right down the street from where the Helpermans are staying, so Spot, as Scott (and the rest of his family) convinces Mary Lou to take him along. Spot becomes a man, but discovers its not everything he ever dreamed of after all.
Nathan Lane
Spot
Shaun Fleming
Leonard
David Ogden Stiers
Jolly
Kelsey Grammer
Dr. Krank
Debra Jo Rupp
Mrs. Helperman
Jerry Stiller
Pretty Boy
Paul Reubens
Dennis
Megan Mullally
Adele
Rob Paulsen
Ian
Wallace Shawn
Principal Strickler
Jay Thomas
Barry Anger
Estelle Harris
Mrs. Boogin
Genie Francis
Marsha
Anthony Geary
John
Rosalyn Landor
Blue Fairy
David Maples
Beefeater
Pamela Adlon
Trevor
Timothy Stack
Daddy
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