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In 1860 Paris, chemist Louis Pasteur is considered a quack within the medical community for advocating that doctors and surgeons wash their hands and boil their instruments to destroy microbes that can kill their patients. He came across this belief when discovering microscopic organisms in sour wine which could be killed if heated sufficiently. The belief among the scientific community at large is that the organisms are the result of disease and not the cause. This belief is despite the fact that 30% of women die in childbirth due to childbed disease, accounting for 20,000 annual deaths in Paris alone. The debate takes Pasteur all the way to a meeting with Emperor Napoleon III and his physician, Dr. Charbonnet, who is one of the leading opponents of Pasteur. Several years later, France is a republic and much of Pasteurs reputation changes as a government sanctioned experiment with anthrax and sheep shows that a vaccine created by Pasteur proves effective. As Pasteur begins work on finding the cause and a cure for rabies, which proves a more difficult challenge, he still has his detractors, including Dr. Charbonnet. This continuing debate brings about his biggest challenge: proving that microbes are the cause of all disease. Through it all, he is supported not only by his family, but Dr. Jean Martel, who was once a junior physician in the emperors court and a physician within the republics government, but who now works with Pasteur and is his son-in-law. But an act of bravado by Charbonnet may ultimately prove to be the breakthrough for which Pasteur is looking. Moving the experimental treatments from animals to humans proves a bigger obstacle, as is Charbonnets need to win at all cost in the court of public opinion.
Hollywood version of famous scientist Louis Pasteur and his work with microbes and their role in disease. Few in the medical community believed Pasteurs theories in this area and after an encounter with the Emperor, leaves Paris. Some years later, officials in Paris hear that there is no anthrax in the area of Arbois. They soon learn that Pasteur is living in there and has in fact developed a vaccine. Skeptics abound but a real-life test proves that his vaccine works. He next sets out to find find the microbe responsible for rabies which proves to be quite elusive. Through a fluke he and his assistant discover that a weakened dose of rabies helps the human immune system create its own antibodies. The approach is far from fully developed but he agrees to treat a young boy who was attacked by a mad dog. The treatment was a great success and further experiments lead to a cure.
Paul Muni
Louis Pasteur
Josephine Hutchinson
Marie Pasteur
Anita Louise
Annette Pasteur
Donald Woods
Dr. Jean Martel
Fritz Leiber
Dr. Charbonnet
Henry O'Neill
Dr. Emile Roux
Porter Hall
Dr. Rossignol
Raymond Brown
Dr. Radisse
Akim Tamiroff
Dr. Zaranoff
Halliwell Hobbes
Dr. Lister
Frank Reicher
Dr. Pfeiffer
Dickie Moore
Joseph Meister
Ruth Robinson
Mrs. Meister
Walter Kingsford
Napoleon III
Iphigenie Castiglioni
Empress Eugénie
Herbert Corthell
Louis Adolphe Thiers - First President Republic of France
Richard Alexander
Burly Farmer
Manson Behfeld
Farm Boy
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