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The spin-off pulls back the curtain on the daily lives of the creatures Hormone Monsters, Depression Kitties, Shame Wizards and many more that help humans journey through every aspect of life from puberty to childbirth to the twilight years. It quickly becomes clear that though the creatures are the protagonists, they have a lot of humanity themselves.
. Aidy Bryant
Emmy Fairfax
Randall Park
Pete Doheny
Keke Palmer
Rochelle Hillhurst
David Thewlis
Lionel St. Swithens
Brandon Kyle Goodman
Walter Las Palmas
Maya Rudolph
Connie LaCienega
Nick Kroll
Maury Beverley
Joe Wengert
Joe
Bobby Cannavale
Gavin Reeves
Hugh Jackman
Dante
Maria Bamford
Tito Taylor Thomas
John Gemberling
Tyler Pico
Gil Ozeri
Gil
Rosie Perez
Petra the Ambition Gremlin
Pamela Adlon
Sonya Poinsettia
Thandiwe Newton
Mona
Ali Wong
Becca Lee
Mike Birbiglia
Barry
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